Epigenetic Modifications of Immune Cells and their Importance for Alloimmunity
Date: September 12, 2018
Time: 02:00PM - 03:00PM
You must be registered to participate!
After participating in this webinar, the learner will be able to:
- Describe an overview of genomic and epigenomic topics that are relevant to alloimmunity.
- Define epigenetics, outline basic concepts and processes.
- Outline examples of DNA methylation controlling T cell function.
- Outline examples of histone modifications controlling T cell function.
- Describe examples of epigenetic factors contributing to organ transplant rejection in rodent models.
- Describe a clinical example of epigenetic drug targeting in allogenic bone marrow transplantation to alleviate GVHD.
- Outline basic concepts in genomics and epigenomics.
- Describe 3-dimensional regulatory architectures of inflammatory genes in T cells.
- Discuss the use of 3D epigenomics to understand the basis of genetic susceptibility to inflammatory disease in humans.