How do alloantibodies induce the pathogenesis of transplant arteriopathy? We have identified a novel NK-mediated pathway that is complement independent and may explain why current immunosuppression does not prevent chronic rejection.
What You'll Take Away from His Talk:
Participants will understand that NK cells are necessary but not sufficient for cardiac allograft vasculopathy.
Participants will understand that complement is not for cardiac allograft vasculopathy.
Participants will understand the potential mechanisms underlying the NK cell pathway of alloantibody-mediated cardiac allograft vasculopathy.