Dr Tambur’s current research focuses on understanding the role of donor-specific HLA antibodies in the context of solid organ, stem cell, and cord blood transplantation with specific emphasis on the significance of antibody affinity and strength. This approach leads to improved virtual crossmatching predictions and enlarged pool of potential donors for renal transplantation. Her most recent work provides a different view of antibody-antigen relationship specifically for HLA-DQ, analyzing the newly emerging concept of HLA epitopes and how it can be applied for determining acceptable and unacceptable HLA mismatches.